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Hypoxia-inducible factor 1α induces osteo/odontoblast differentiation of human dental pulp stem cells via Wnt/β-catenin transcriptional cofactor BCL9
Accelerated dental pulp mineralization is a common complication in avulsed/luxated teeth, although the mechanisms underlying this remain unclear. We hypothesized that hypoxia due to vascular severance may induce osteo/odontoblast differentiation of dental pulp stem cells (DPSCs). This study examined...
Autores principales: | Orikasa, Shion, Kawashima, Nobuyuki, Tazawa, Kento, Hashimoto, Kentaro, Sunada-Nara, Keisuke, Noda, Sonoko, Fujii, Mayuko, Akiyama, Tetsu, Okiji, Takashi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758693/ https://www.ncbi.nlm.nih.gov/pubmed/35027586 http://dx.doi.org/10.1038/s41598-021-04453-8 |
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