Automated light-induced synthesis of (89)Zr-radiolabeled antibodies for immuno-positron emission tomography

Clinical production of (89)Zr-radiolabeled antibodies ((89)Zr-mAbs) for positron emission tomography imaging relies on the pre-conjugation of desferrioxamine B (DFO) to the purified protein, followed by isolation and characterization of the functionalized intermediate, and then manual radiosynthesis...

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Detalles Bibliográficos
Autores principales: Klingler, Simon, Holland, Jason P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758695/
https://www.ncbi.nlm.nih.gov/pubmed/35027637
http://dx.doi.org/10.1038/s41598-021-04626-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758695/
https://www.ncbi.nlm.nih.gov/pubmed/35027637
http://dx.doi.org/10.1038/s41598-021-04626-5

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