Linking DNA repair and cell cycle progression through serine ADP-ribosylation of histones

Although serine ADP-ribosylation (Ser-ADPr) by Poly(ADP-ribose)-polymerases is a cornerstone of the DNA damage response, how this regulates DNA repair and genome stability is unknown. Here, we exploit the ability to manipulate histone genes in Dictyostelium to identify that ADPr of the histone varia...

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Detalles Bibliográficos
Autores principales: Brustel, Julien, Muramoto, Tetsuya, Fumimoto, Kazuki, Ellins, Jessica, Pears, Catherine J., Lakin, Nicholas D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758696/
https://www.ncbi.nlm.nih.gov/pubmed/35027540
http://dx.doi.org/10.1038/s41467-021-27867-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758696/
https://www.ncbi.nlm.nih.gov/pubmed/35027540
http://dx.doi.org/10.1038/s41467-021-27867-4

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