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Linking DNA repair and cell cycle progression through serine ADP-ribosylation of histones
Although serine ADP-ribosylation (Ser-ADPr) by Poly(ADP-ribose)-polymerases is a cornerstone of the DNA damage response, how this regulates DNA repair and genome stability is unknown. Here, we exploit the ability to manipulate histone genes in Dictyostelium to identify that ADPr of the histone varia...
Autores principales: | Brustel, Julien, Muramoto, Tetsuya, Fumimoto, Kazuki, Ellins, Jessica, Pears, Catherine J., Lakin, Nicholas D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758696/ https://www.ncbi.nlm.nih.gov/pubmed/35027540 http://dx.doi.org/10.1038/s41467-021-27867-4 |
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