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USP15 and USP4 facilitate lung cancer cell proliferation by regulating the alternative splicing of SRSF1

The deubiquitinating enzyme USP15 is implicated in several human cancers by regulating different cellular processes, including splicing regulation. However, the underlying molecular mechanisms of its functional relevance and the successive roles in enhanced tumorigenesis remain ambiguous. Here, we f...

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Detalles Bibliográficos
Autores principales: Das, Tanuza, Lee, Eun-Young, You, Hye Jin, Kim, Eunice EunKyeong, Song, Eun Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758713/
https://www.ncbi.nlm.nih.gov/pubmed/35027535
http://dx.doi.org/10.1038/s41420-022-00820-0