Pterostilbene downregulates BCR/ABL and induces apoptosis of T315I-mutated BCR/ABL-positive leukemic cells

In this study, we examined the antileukemic effects of pterostilbene, a natural methylated polyphenol analog of resveratrol that is predominantly found in berries and nuts, using various human and murine leukemic cells, as well as bone marrow samples obtained from patients with leukemia. Pterostilbe...

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Detalles Bibliográficos
Autores principales: Kawakami, Shohei, Tsuma-Kaneko, Mitsuyo, Sawanobori, Masakazu, Uno, Tomoko, Nakamura, Yoshihiko, Matsuzawa, Hideyuki, Suzuki, Rikio, Onizuka, Makoto, Yahata, Takashi, Naka, Kazuhito, Ando, Kiyoshi, Kawada, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758722/
https://www.ncbi.nlm.nih.gov/pubmed/35027628
http://dx.doi.org/10.1038/s41598-021-04654-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758722/
https://www.ncbi.nlm.nih.gov/pubmed/35027628
http://dx.doi.org/10.1038/s41598-021-04654-1

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