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Stem-like breast cancer cells in the activated state resist genetic stress via TGFBI-ZEB1

Breast cancer cells with stem-like properties are critical for tumor progression, yet much about these cells remains unknown. Here, we characterize a population of stem-like breast cancer cells expressing the integrin αvβ3 as transcriptionally related to activated stem/basal cells in the normal huma...

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Detalles Bibliográficos
Autores principales: Sun, Qi, Wang, Yufen, Officer, Adam, Pecknold, Brianna, Lee, Garrett, Harismendy, Olivier, Desgrosellier, Jay S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758745/
https://www.ncbi.nlm.nih.gov/pubmed/35027548
http://dx.doi.org/10.1038/s41523-021-00375-w