HBXIP induces anoikis resistance by forming a reciprocal feedback loop with Nrf2 to maintain redox homeostasis and stabilize Prdx1 in breast cancer

Anoikis resistance is an essential prerequisite for tumor metastasis, but the underlying molecular mechanisms remain unknown. Herein, we report that the oncoprotein hepatitis B X-interacting protein (HBXIP) is prominently upregulated in breast cancer cells following ECM detachment. Altering HBXIP ex...

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Detalles Bibliográficos
Autores principales: Zhou, Xiaolei, Li, Li, Guo, Xin, Zhang, Chunxiao, Du, Yanyan, Li, Tianming, Tong, Kaiqing, Zhu, Chongyue, Wang, Zijin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758767/
https://www.ncbi.nlm.nih.gov/pubmed/35027562
http://dx.doi.org/10.1038/s41523-021-00374-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758767/
https://www.ncbi.nlm.nih.gov/pubmed/35027562
http://dx.doi.org/10.1038/s41523-021-00374-x

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