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MiR-135b-5p is an oncogene in pancreatic cancer to regulate GPRC5A expression by targeting transcription factor KLF4

KLF4 is implicated in tumor progression of pancreatic cancer, but the molecular regulatory mechanism of KLF4 needs to be further specified. We aimed to probe molecular regulatory mechanism of KLF4 in malignant progression of pancreatic cancer. qRT-PCR or western blot was completed to test levels of...

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Detalles Bibliográficos
Autores principales: Liu, Daren, Jin, Yun, Wu, Jinhong, Zhu, Huanbing, Ye, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758781/
https://www.ncbi.nlm.nih.gov/pubmed/35027543
http://dx.doi.org/10.1038/s41420-022-00814-y