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Associations between body composition, fat distribution and metabolic consequences of excess adiposity with severe COVID-19 outcomes: observational study and Mendelian randomisation analysis

BACKGROUND: Higher body mass index (BMI) and metabolic consequences of excess weight are associated with increased risk of severe COVID-19, though their mediating pathway is unclear. METHODS: A prospective cohort study included 435,504 UK Biobank participants. A two-sample Mendelian randomisation (M...

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Detalles Bibliográficos
Autores principales: Gao, Min, Wang, Qin, Piernas, Carmen, Astbury, Nerys M., Jebb, Susan A., Holmes, Michael V., Aveyard, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758930/
https://www.ncbi.nlm.nih.gov/pubmed/35031696
http://dx.doi.org/10.1038/s41366-021-01054-3