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Associations between body composition, fat distribution and metabolic consequences of excess adiposity with severe COVID-19 outcomes: observational study and Mendelian randomisation analysis
BACKGROUND: Higher body mass index (BMI) and metabolic consequences of excess weight are associated with increased risk of severe COVID-19, though their mediating pathway is unclear. METHODS: A prospective cohort study included 435,504 UK Biobank participants. A two-sample Mendelian randomisation (M...
Autores principales: | Gao, Min, Wang, Qin, Piernas, Carmen, Astbury, Nerys M., Jebb, Susan A., Holmes, Michael V., Aveyard, Paul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758930/ https://www.ncbi.nlm.nih.gov/pubmed/35031696 http://dx.doi.org/10.1038/s41366-021-01054-3 |
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