Haploid mouse germ cell precursors from embryonic stem cells reveal Xist activation from a single X chromosome

Mammalian haploid cells have applications for genetic screening and substituting gametic genomes. Here, we characterize a culture system for obtaining haploid primordial germ cell-like cells (PGCLCs) from haploid mouse embryonic stem cells (ESCs). We find that haploid cells show predisposition for P...

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Detalles Bibliográficos
Autores principales: Aizawa, Eishi, Kaufmann, Corinne, Sting, Sarah, Boigner, Sarah, Freimann, Remo, Di Minin, Giulio, Wutz, Anton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758942/
https://www.ncbi.nlm.nih.gov/pubmed/34919812
http://dx.doi.org/10.1016/j.stemcr.2021.11.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758942/
https://www.ncbi.nlm.nih.gov/pubmed/34919812
http://dx.doi.org/10.1016/j.stemcr.2021.11.006

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