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Haploid mouse germ cell precursors from embryonic stem cells reveal Xist activation from a single X chromosome

Mammalian haploid cells have applications for genetic screening and substituting gametic genomes. Here, we characterize a culture system for obtaining haploid primordial germ cell-like cells (PGCLCs) from haploid mouse embryonic stem cells (ESCs). We find that haploid cells show predisposition for P...

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Detalles Bibliográficos
Autores principales:	Aizawa, Eishi, Kaufmann, Corinne, Sting, Sarah, Boigner, Sarah, Freimann, Remo, Di Minin, Giulio, Wutz, Anton
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758942/ https://www.ncbi.nlm.nih.gov/pubmed/34919812 http://dx.doi.org/10.1016/j.stemcr.2021.11.006

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