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A functional hiPSC-cortical neuron differentiation and maturation model and its application to neurological disorders

The maturation and functional characteristics of human induced pluripotent stem cell (hiPSC)-cortical neurons has not been fully documented. This study developed a phenotypic model of hiPSC-derived cortical neurons, characterized their maturation process, and investigated its application for disease...

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Detalles Bibliográficos
Autores principales: Autar, Kaveena, Guo, Xiufang, Rumsey, John W., Long, Christopher J., Akanda, Nesar, Jackson, Max, Narasimhan, Narasimhan S., Caneus, Julbert, Morgan, Dave, Hickman, James J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758945/
https://www.ncbi.nlm.nih.gov/pubmed/34942087
http://dx.doi.org/10.1016/j.stemcr.2021.11.009