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A novel two-factor monosynaptic TRIO tracing method for assessment of circuit integration of hESC-derived dopamine transplants

Transplantation in Parkinson's disease using human embryonic stem cell (hESC)-derived dopaminergic (DA) neurons is a promising future treatment option. However, many of the mechanisms that govern their differentiation, maturation, and integration into the host circuitry remain elusive. Here, we...

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Detalles Bibliográficos
Autores principales: Aldrin-Kirk, Patrick, Åkerblom, Malin, Cardoso, Tiago, Nolbrant, Sara, Adler, Andrew F., Liu, Xiaohe, Heuer, Andreas, Davidsson, Marcus, Parmar, Malin, Björklund, Tomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758947/
https://www.ncbi.nlm.nih.gov/pubmed/34971563
http://dx.doi.org/10.1016/j.stemcr.2021.11.014