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A novel two-factor monosynaptic TRIO tracing method for assessment of circuit integration of hESC-derived dopamine transplants
Transplantation in Parkinson's disease using human embryonic stem cell (hESC)-derived dopaminergic (DA) neurons is a promising future treatment option. However, many of the mechanisms that govern their differentiation, maturation, and integration into the host circuitry remain elusive. Here, we...
Autores principales: | Aldrin-Kirk, Patrick, Åkerblom, Malin, Cardoso, Tiago, Nolbrant, Sara, Adler, Andrew F., Liu, Xiaohe, Heuer, Andreas, Davidsson, Marcus, Parmar, Malin, Björklund, Tomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758947/ https://www.ncbi.nlm.nih.gov/pubmed/34971563 http://dx.doi.org/10.1016/j.stemcr.2021.11.014 |
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