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Lipogenesis inhibitors: therapeutic opportunities and challenges

Fatty acids are essential for survival, acting as bioenergetic substrates, structural components and signalling molecules. Given their vital role, cells have evolved mechanisms to generate fatty acids from alternative carbon sources, through a process known as de novo lipogenesis (DNL). Despite the...

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Detalles Bibliográficos
Autores principales: Batchuluun, Battsetseg, Pinkosky, Stephen L., Steinberg, Gregory R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758994/
https://www.ncbi.nlm.nih.gov/pubmed/35031766
http://dx.doi.org/10.1038/s41573-021-00367-2