Lysosome-targeted drug combination induces multiple organelle dysfunctions and non-canonical death in pancreatic cancer cells

Pancreatic cancer is one of the leading causes of cancer-related mortality and has the lowest 5-year survival rate. Therefore, novel strategies are urgently required to treat pancreatic cancer. Pancreatic ductal adenocarcinoma (PDAC) cells rely on enhanced lysosomal function for survival and prolife...

Descripción completa

Detalles Bibliográficos
Autores principales: Suzuki, Sumire, Ogawa, Masato, Miyazaki, Masaya, Ota, Kohki, Kazama, Hiromi, Hirota, Ayako, Takano, Naoharu, Hiramoto, Masaki, Miyazawa, Keisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8759104/
https://www.ncbi.nlm.nih.gov/pubmed/34958115
http://dx.doi.org/10.3892/or.2021.8251

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8759104/
https://www.ncbi.nlm.nih.gov/pubmed/34958115
http://dx.doi.org/10.3892/or.2021.8251

Ejemplares similares