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Lysosome-targeted drug combination induces multiple organelle dysfunctions and non-canonical death in pancreatic cancer cells

Pancreatic cancer is one of the leading causes of cancer-related mortality and has the lowest 5-year survival rate. Therefore, novel strategies are urgently required to treat pancreatic cancer. Pancreatic ductal adenocarcinoma (PDAC) cells rely on enhanced lysosomal function for survival and prolife...

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Detalles Bibliográficos
Autores principales:	Suzuki, Sumire, Ogawa, Masato, Miyazaki, Masaya, Ota, Kohki, Kazama, Hiromi, Hirota, Ayako, Takano, Naoharu, Hiramoto, Masaki, Miyazawa, Keisuke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8759104/ https://www.ncbi.nlm.nih.gov/pubmed/34958115 http://dx.doi.org/10.3892/or.2021.8251

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