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Defining the AHR-regulated transcriptome in NK cells reveals gene expression programs relevant to development and function

The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor that regulates cellular processes in cancer and immunity, including innate immune cell development and effector function. However, the transcriptional repertoire through which AHR mediates these effects remains largely un...

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Detalles Bibliográficos
Autores principales: Trikha, Prashant, Moseman, Jena E., Thakkar, Aarohi, Campbell, Amanda R., Elmas, Ezgi, Foltz, Jennifer A., Chakravarti, Nitin, Fitch, James R., Mardis, Elaine R., Lee, Dean A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8759121/
https://www.ncbi.nlm.nih.gov/pubmed/34559190
http://dx.doi.org/10.1182/bloodadvances.2021004533