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Polyphosphate expression by cancer cell extracellular vesicles mediates binding of factor XII and contact activation

Extracellular vesicles (EV) have been implicated in diverse biological processes, including intracellular communication, transport of nucleic acids, and regulation of vascular function. Levels of EVs are elevated in cancer, and studies suggest that EV may stimulate thrombosis in patients with cancer...

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Detalles Bibliográficos
Autores principales: Shim, Young Jun, Chatterjee, Victor, Swaidani, Shadi, Alluri, Ravi Kumar, Kundu, Suman, Merkulova, Alona, Angelini, Dana, You, Dewen, Whitney, Samantha A., Feener, Edward P., Barnard, John, Schmaier, Alvin H., Khorana, Alok A., McCrae, Keith R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8759128/
https://www.ncbi.nlm.nih.gov/pubmed/34597365
http://dx.doi.org/10.1182/bloodadvances.2021005116