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GM-CSF production by non-classical monocytes controls antagonistic LPS-driven functions in allergic inflammation

Lipopolysaccharide (LPS) can either promote or prevent T helper 2 (Th2) cell allergic responses. However, the underlying mechanism remains unknown. We show here that LPS activity switches from pro-pathogenic to protective depending on the production of granulocyte-macrophage colony-stimulating facto...

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Detalles Bibliográficos
Autores principales: Kaur, Kamaljeet, Bachus, Holly, Lewis, Crystal, Papillion, Amber M., Rosenberg, Alexander F., Ballesteros-Tato, André, León, Beatriz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8759241/
https://www.ncbi.nlm.nih.gov/pubmed/34965421
http://dx.doi.org/10.1016/j.celrep.2021.110178