N6-methyladenosine upregulates miR-181d-5p in exosomes derived from cancer-associated fibroblasts to inhibit 5-FU sensitivity by targeting NCALD in colorectal cancer

Resistance to 5-Fluorouracil (5-FU) is a frequent occurrence in patients with colorectal cancer (CRC). MicroRNAs (miRNAs) from cancer-associated fibroblasts (CAFs)-secreted exosomes have been associated with 5-FU sensitivity. The potential molecular mechanism of CAFs-exosomal miRNAs in CRC remains u...

Descripción completa

Detalles Bibliográficos
Autores principales: Pan, Shengli, Deng, Yingying, Fu, Jun, Zhang, Yuhao, Zhang, Zhijin, Qin, Xianju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8759347/
https://www.ncbi.nlm.nih.gov/pubmed/35014676
http://dx.doi.org/10.3892/ijo.2022.5304

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8759347/
https://www.ncbi.nlm.nih.gov/pubmed/35014676
http://dx.doi.org/10.3892/ijo.2022.5304

Ejemplares similares