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N6-methyladenosine upregulates miR-181d-5p in exosomes derived from cancer-associated fibroblasts to inhibit 5-FU sensitivity by targeting NCALD in colorectal cancer

Resistance to 5-Fluorouracil (5-FU) is a frequent occurrence in patients with colorectal cancer (CRC). MicroRNAs (miRNAs) from cancer-associated fibroblasts (CAFs)-secreted exosomes have been associated with 5-FU sensitivity. The potential molecular mechanism of CAFs-exosomal miRNAs in CRC remains u...

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Detalles Bibliográficos
Autores principales:	Pan, Shengli, Deng, Yingying, Fu, Jun, Zhang, Yuhao, Zhang, Zhijin, Qin, Xianju
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8759347/ https://www.ncbi.nlm.nih.gov/pubmed/35014676 http://dx.doi.org/10.3892/ijo.2022.5304

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