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Borrowing of information across patient subgroups in a basket trial based on distributional discrepancy

Basket trials have emerged as a new class of efficient approaches in oncology to evaluate a new treatment in several patient subgroups simultaneously. In this article, we extend the key ideas to disease areas outside of oncology, developing a robust Bayesian methodology for randomized, placebo-contr...

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Detalles Bibliográficos
Autores principales: Zheng, Haiyan, Wason, James M S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8759447/
https://www.ncbi.nlm.nih.gov/pubmed/32380518
http://dx.doi.org/10.1093/biostatistics/kxaa019