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Borrowing of information across patient subgroups in a basket trial based on distributional discrepancy
Basket trials have emerged as a new class of efficient approaches in oncology to evaluate a new treatment in several patient subgroups simultaneously. In this article, we extend the key ideas to disease areas outside of oncology, developing a robust Bayesian methodology for randomized, placebo-contr...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8759447/ https://www.ncbi.nlm.nih.gov/pubmed/32380518 http://dx.doi.org/10.1093/biostatistics/kxaa019 |