cADPR induced calcium influx mediates axonal degeneration caused by paclitaxel

Activation of the NAD hydrolase domain of Sarm1 mediates axonal degeneration caused by chemotherapy drugs, but the downstream events are unknown. In this issue, Li and colleagues (2021. J. Cell Biol. https://doi.org/10.1083/jcb.202106080) demonstrate that cADPR, a breakdown product of NAD, mediates...

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Detalles Bibliográficos
Autor principal: Höke, Ahmet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Spotlight
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8759606/
https://www.ncbi.nlm.nih.gov/pubmed/35019936
http://dx.doi.org/10.1083/jcb.202112021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8759606/
https://www.ncbi.nlm.nih.gov/pubmed/35019936
http://dx.doi.org/10.1083/jcb.202112021

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