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Viral RNA N(6)-methyladenosine modification modulates both innate and adaptive immune responses of human respiratory syncytial virus

Human respiratory syncytial virus (RSV) is the leading cause of respiratory tract infections in humans. A well-known challenge in the development of a live attenuated RSV vaccine is that interferon (IFN)-mediated antiviral responses are strongly suppressed by RSV nonstructural proteins which, in tur...

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Detalles Bibliográficos
Autores principales: Xue, Miaoge, Zhang, Yuexiu, Wang, Haitao, Kairis, Elizabeth L., Lu, Mijia, Ahmad, Sadeem, Attia, Zayed, Harder, Olivia, Zhang, Zijie, Wei, Jiangbo, Chen, Phylip, Gao, Youling, Peeples, Mark E., Sharma, Amit, Boyaka, Prosper, He, Chuan, Hur, Sun, Niewiesk, Stefan, Li, Jianrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8759664/
https://www.ncbi.nlm.nih.gov/pubmed/34929018
http://dx.doi.org/10.1371/journal.ppat.1010142