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Reliable chromatographic assay for measuring of indoleamine 2,3-dioxygenase 1 (IDO1) activity in human cancer cells

The kynurenine pathway is the major tryptophan degradation routes generating bioactive compounds important in physiology and diseases. Depending on cell type it is initiated enzymatically by tryptophan-2,3-dioxygenase (TDO) or indoleamine-2,3-dioxygenase 1 and 2 (IDO1 and IDO2) to yield N-formylkynu...

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Detalles Bibliográficos
Autores principales: Sadok, Ilona, Rachwał, Kamila, Jonik, Ilona, Staniszewska, Magdalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8759722/
https://www.ncbi.nlm.nih.gov/pubmed/33541164
http://dx.doi.org/10.1080/14756366.2021.1882451