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Differential voltage-dependent modulation of the ACh-gated K(+) current by adenosine and acetylcholine
Inhibitory regulation of the heart is determined by both cholinergic M(2) receptors (M(2)R) and adenosine A(1) receptors (A(1)R) that activate the same signaling pathway, the ACh-gated inward rectifier K(+) (K(ACh)) channels via G(i/o) proteins. Previously, we have shown that the agonist-specific vo...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8759768/ https://www.ncbi.nlm.nih.gov/pubmed/35030226 http://dx.doi.org/10.1371/journal.pone.0261960 |