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Differential voltage-dependent modulation of the ACh-gated K(+) current by adenosine and acetylcholine

Inhibitory regulation of the heart is determined by both cholinergic M(2) receptors (M(2)R) and adenosine A(1) receptors (A(1)R) that activate the same signaling pathway, the ACh-gated inward rectifier K(+) (K(ACh)) channels via G(i/o) proteins. Previously, we have shown that the agonist-specific vo...

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Detalles Bibliográficos
Autores principales: López-Serrano, Ana Laura, Zamora-Cárdenas, Rodrigo, Aréchiga-Figueroa, Iván A., Salazar-Fajardo, Pedro D., Ferrer, Tania, Alamilla, Javier, Sánchez-Chapula, José A., Navarro-Polanco, Ricardo A., Moreno-Galindo, Eloy G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8759768/
https://www.ncbi.nlm.nih.gov/pubmed/35030226
http://dx.doi.org/10.1371/journal.pone.0261960