SARS-CoV-2–specific memory B cells can persist in the elderly who have lost detectable neutralizing antibodies

Memory B cells (MBCs) can provide a recall response able to supplement waning antibodies (Abs) with an affinity-matured response better able to neutralize variant viruses. We studied a cohort of elderly care home residents and younger staff (median age of 87 years and 56 years, respectively), who ha...

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Detalles Bibliográficos
Autores principales: Jeffery-Smith, Anna, Burton, Alice R., Lens, Sabela, Rees-Spear, Chloe, Davies, Jessica, Patel, Monika, Gopal, Robin, Muir, Luke, Aiano, Felicity, Doores, Katie J., Chow, J. Yimmy, Ladhani, Shamez N., Zambon, Maria, McCoy, Laura E., Maini, Mala K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8759779/
https://www.ncbi.nlm.nih.gov/pubmed/34843448
http://dx.doi.org/10.1172/JCI152042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8759779/
https://www.ncbi.nlm.nih.gov/pubmed/34843448
http://dx.doi.org/10.1172/JCI152042

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