β3-Adrenergic receptor downregulation leads to adipocyte catecholamine resistance in obesity

The dysregulation of energy homeostasis in obesity involves multihormone resistance. Although leptin and insulin resistance have been well characterized, catecholamine resistance remains largely unexplored. Murine β3-adrenergic receptor expression in adipocytes is orders of magnitude higher compared...

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Detalles Bibliográficos
Autores principales: Valentine, Joseph M., Ahmadian, Maryam, Keinan, Omer, Abu-Odeh, Mohammad, Zhao, Peng, Zhou, Xin, Keller, Mark P., Gao, Hui, Yu, Ruth T., Liddle, Christopher, Downes, Michael, Zhang, Jin, Lusis, Aldons J., Attie, Alan D., Evans, Ronald M., Rydén, Mikael, Saltiel, Alan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8759781/
https://www.ncbi.nlm.nih.gov/pubmed/34847077
http://dx.doi.org/10.1172/JCI153357

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8759781/
https://www.ncbi.nlm.nih.gov/pubmed/34847077
http://dx.doi.org/10.1172/JCI153357

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