B cell receptor isotypes differentially associate with cell signaling, kinetics, and outcome in chronic lymphocytic leukemia

In chronic lymphocytic leukemia (CLL), the B cell receptor (BCR) plays a critical role in disease development and progression, as indicated by the therapeutic efficacy of drugs blocking BCR signaling. However, the mechanism(s) underlying BCR responsiveness are not completely defined. Selective engag...

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Detalles Bibliográficos
Autores principales: Mazzarello, Andrea N., Gentner-Göbel, Eva, Dühren-von Minden, Marcus, Tarasenko, Tatyana N., Nicolò, Antonella, Ferrer, Gerardo, Vergani, Stefano, Liu, Yun, Bagnara, Davide, Rai, Kanti R., Burger, Jan A., McGuire, Peter J., Maity, Palash C., Jumaa, Hassan, Chiorazzi, Nicholas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8759784/
https://www.ncbi.nlm.nih.gov/pubmed/34813501
http://dx.doi.org/10.1172/JCI149308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8759784/
https://www.ncbi.nlm.nih.gov/pubmed/34813501
http://dx.doi.org/10.1172/JCI149308

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