Alzheimer’s disease and progressive supranuclear palsy share similar transcriptomic changes in distinct brain regions

Vast numbers of differentially expressed genes and perturbed networks have been identified in Alzheimer’s disease (AD), however, neither disease nor brain region specificity of these transcriptome alterations has been explored. Using RNA-Seq data from 231 temporal cortex and 224 cerebellum samples f...

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Detalles Bibliográficos
Autores principales: Wang, Xue, Allen, Mariet, İş, Özkan, Reddy, Joseph S., Tutor-New, Frederick Q., Castanedes Casey, Monica, Carrasquillo, Minerva M., Oatman, Stephanie R., Min, Yuhao, Asmann, Yan W., Funk, Cory, Nguyen, Thuy, Ho, Charlotte C.G., Malphrus, Kimberly G., Seyfried, Nicholas T., Levey, Allan I., Younkin, Steven G., Murray, Melissa E., Dickson, Dennis W., Price, Nathan D., Golde, Todd E., Ertekin-Taner, Nilüfer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Concise Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8759790/
https://www.ncbi.nlm.nih.gov/pubmed/34813500
http://dx.doi.org/10.1172/JCI149904

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8759790/
https://www.ncbi.nlm.nih.gov/pubmed/34813500
http://dx.doi.org/10.1172/JCI149904

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