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Alzheimer’s disease and progressive supranuclear palsy share similar transcriptomic changes in distinct brain regions
Vast numbers of differentially expressed genes and perturbed networks have been identified in Alzheimer’s disease (AD), however, neither disease nor brain region specificity of these transcriptome alterations has been explored. Using RNA-Seq data from 231 temporal cortex and 224 cerebellum samples f...
Autores principales: | Wang, Xue, Allen, Mariet, İş, Özkan, Reddy, Joseph S., Tutor-New, Frederick Q., Castanedes Casey, Monica, Carrasquillo, Minerva M., Oatman, Stephanie R., Min, Yuhao, Asmann, Yan W., Funk, Cory, Nguyen, Thuy, Ho, Charlotte C.G., Malphrus, Kimberly G., Seyfried, Nicholas T., Levey, Allan I., Younkin, Steven G., Murray, Melissa E., Dickson, Dennis W., Price, Nathan D., Golde, Todd E., Ertekin-Taner, Nilüfer |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8759790/ https://www.ncbi.nlm.nih.gov/pubmed/34813500 http://dx.doi.org/10.1172/JCI149904 |
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