Coenzyme Q(0) Inhibits NLRP3 Inflammasome Activation through Mitophagy Induction in LPS/ATP-Stimulated Macrophages

Coenzyme Q (CoQ) analogs with a variable number of isoprenoid units have exhibited as anti-inflammatory as well as antioxidant molecules. Using novel quinone derivative CoQ(0) (2,3-dimethoxy-5-methyl-1,4-benzoquinone, zero side chain isoprenoid), we studied its molecular activities against LPS/ATP-i...

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Detalles Bibliográficos
Autores principales: Hseu, You-Cheng, Tseng, Yu-Fang, Pandey, Sudhir, Shrestha, Sirjana, Lin, Kai-Yuan, Lin, Cheng-Wen, Lee, Chuan-Chen, Huang, Sheng-Teng, Yang, Hsin-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8759827/
https://www.ncbi.nlm.nih.gov/pubmed/35035661
http://dx.doi.org/10.1155/2022/4266214

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8759827/
https://www.ncbi.nlm.nih.gov/pubmed/35035661
http://dx.doi.org/10.1155/2022/4266214

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