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Omega-3 polyunsaturated fatty acids protect against inflammation through production of LOX and CYP450 lipid mediators: relevance for major depression and for human hippocampal neurogenesis

Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) can exert antidepressant, anti-inflammatory and neuroprotective properties, but the exact molecular mechanism underlying their effects is still not fully understood. We conducted both in vitro and clinical investigations to test which EPA or...

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Detalles Bibliográficos
Autores principales: Borsini, Alessandra, Nicolaou, Anna, Camacho-Muñoz, Dolores, Kendall, Alexandra C., Di Benedetto, Maria Grazia, Giacobbe, Juliette, Su, Kuan-Pin, Pariante, Carmine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760043/
https://www.ncbi.nlm.nih.gov/pubmed/34131267
http://dx.doi.org/10.1038/s41380-021-01160-8