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CCL5 promotion of bioenergy metabolism is crucial for hippocampal synapse complex and memory formation

Glucoregulatory efficiency and ATP production are key regulators for neuronal plasticity and memory formation. Besides its chemotactic and neuroinflammatory functions, the CC chemokine––CCL5 displays neurotrophic activity. We found impaired learning-memory and cognition in CCL5-knockout mice at 4 mo...

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Detalles Bibliográficos
Autores principales: Ajoy, Reni, Lo, Yu-Chun, Ho, Man-Hau, Chen, You-Yin, Wang, Yun, Chen, Yuan-Hao, Jing-Yuan, Chiu, Changou, Chun Austin, Hsiung, Yuan-Chin, Chen, Hui-Min, Chang, Tzu-Hao, Lee, Cheng-Yang, Chiang, Yung-Hsiao, Chang, Wen-Chang, Hoffer, Barry, Chou, Szu-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760051/
https://www.ncbi.nlm.nih.gov/pubmed/33931731
http://dx.doi.org/10.1038/s41380-021-01103-3