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CCL5 promotion of bioenergy metabolism is crucial for hippocampal synapse complex and memory formation
Glucoregulatory efficiency and ATP production are key regulators for neuronal plasticity and memory formation. Besides its chemotactic and neuroinflammatory functions, the CC chemokine––CCL5 displays neurotrophic activity. We found impaired learning-memory and cognition in CCL5-knockout mice at 4 mo...
Autores principales: | Ajoy, Reni, Lo, Yu-Chun, Ho, Man-Hau, Chen, You-Yin, Wang, Yun, Chen, Yuan-Hao, Jing-Yuan, Chiu, Changou, Chun Austin, Hsiung, Yuan-Chin, Chen, Hui-Min, Chang, Tzu-Hao, Lee, Cheng-Yang, Chiang, Yung-Hsiao, Chang, Wen-Chang, Hoffer, Barry, Chou, Szu-Yi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760051/ https://www.ncbi.nlm.nih.gov/pubmed/33931731 http://dx.doi.org/10.1038/s41380-021-01103-3 |
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