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Microglia-specific knock-down of Bmal1 improves memory and protects mice from high fat diet-induced obesity
Microglia play a critical role in maintaining neural function. While microglial activity follows a circadian rhythm, it is not clear how this intrinsic clock relates to their function, especially in stimulated conditions such as in the control of systemic energy homeostasis or memory formation. In t...
Autores principales: | Wang, Xiao-Lan, Kooijman, Sander, Gao, Yuanqing, Tzeplaeff, Laura, Cosquer, Brigitte, Milanova, Irina, Wolff, Samantha E. C., Korpel, Nikita, Champy, Marie-France, Petit-Demoulière, Benoit, Goncalves Da Cruz, Isabelle, Sorg-Guss, Tania, Rensen, Patrick C. N., Cassel, Jean-Christophe, Kalsbeek, Andries, Boutillier, Anne-Laurence, Yi, Chun-Xia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760060/ https://www.ncbi.nlm.nih.gov/pubmed/34050326 http://dx.doi.org/10.1038/s41380-021-01169-z |
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