Lithium increases mitochondrial respiration in iPSC-derived neural precursor cells from lithium responders

Lithium (Li), valproate (VPA) and lamotrigine (LTG) are commonly used to treat bipolar disorder (BD). While their clinical efficacy is well established, the mechanisms of action at the molecular level are still incompletely understood. Here we investigated the molecular effects of Li, LTG and VPA tr...

Descripción completa

Detalles Bibliográficos
Autores principales: Osete, Jordi Requena, Akkouh, Ibrahim A., de Assis, Denis Reis, Szabo, Attila, Frei, Evgeniia, Hughes, Timothy, Smeland, Olav B., Steen, Nils Eiel, Andreassen, Ole A., Djurovic, Srdjan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760072/
https://www.ncbi.nlm.nih.gov/pubmed/34075196
http://dx.doi.org/10.1038/s41380-021-01164-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760072/
https://www.ncbi.nlm.nih.gov/pubmed/34075196
http://dx.doi.org/10.1038/s41380-021-01164-4

Ejemplares similares