RAB39B-mediated trafficking of the GluA2-AMPAR subunit controls dendritic spine maturation and intellectual disability-related behaviour

Mutations in the RAB39B gene cause X-linked intellectual disability (XLID), comorbid with autism spectrum disorders or early Parkinson’s disease. One of the functions of the neuronal small GTPase RAB39B is to drive GluA2/GluA3 α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR) mat...

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Detalles Bibliográficos
Autores principales: Mignogna, Maria Lidia, Musardo, Stefano, Ranieri, Giulia, Gelmini, Susanna, Espinosa, Pedro, Marra, Paolo, Belloli, Sara, Murtaj, Valentina, Moresco, Rosa Maria, Bellone, Camilla, D’Adamo, Patrizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760075/
https://www.ncbi.nlm.nih.gov/pubmed/34035473
http://dx.doi.org/10.1038/s41380-021-01155-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760075/
https://www.ncbi.nlm.nih.gov/pubmed/34035473
http://dx.doi.org/10.1038/s41380-021-01155-5

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