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Diverse classes of constraints enable broader applicability of a linear programming-based dynamic metabolic modeling framework

Current metabolic modeling tools suffer from a variety of limitations, from scalability to simplifying assumptions, that preclude their use in many applications. We recently created a modeling framework, Linear Kinetics-Dynamic Flux Balance Analysis (LK-DFBA), that addresses a key gap: capturing met...

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Detalles Bibliográficos
Autores principales: Lee, Justin Y., Styczynski, Mark P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760257/
https://www.ncbi.nlm.nih.gov/pubmed/35031616
http://dx.doi.org/10.1038/s41598-021-03934-0