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Diverse classes of constraints enable broader applicability of a linear programming-based dynamic metabolic modeling framework
Current metabolic modeling tools suffer from a variety of limitations, from scalability to simplifying assumptions, that preclude their use in many applications. We recently created a modeling framework, Linear Kinetics-Dynamic Flux Balance Analysis (LK-DFBA), that addresses a key gap: capturing met...
Autores principales: | Lee, Justin Y., Styczynski, Mark P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760257/ https://www.ncbi.nlm.nih.gov/pubmed/35031616 http://dx.doi.org/10.1038/s41598-021-03934-0 |
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