Extendable stapling of unprotected peptides by crosslinking two amines with o-phthalaldehyde

Peptide modification methods that do not rely on the cysteine residue are underdeveloped, and their development could greatly expand the current toolbox for peptide chemistry. During the course of preliminary investigations into the classical ortho-phthalaldehyde (OPA)-amine-thiol condensation react...

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Detalles Bibliográficos
Autores principales: Li, Bo, Wang, Lan, Chen, Xiangxiang, Chu, Xin, Tang, Hong, Zhang, Jie, He, Gang, Li, Li, Chen, Gong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760283/
https://www.ncbi.nlm.nih.gov/pubmed/35031608
http://dx.doi.org/10.1038/s41467-022-27985-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760283/
https://www.ncbi.nlm.nih.gov/pubmed/35031608
http://dx.doi.org/10.1038/s41467-022-27985-7

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