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Inhibition of Rac1 attenuates radiation-induced lung injury while suppresses lung tumor in mice

The lung is one of the most sensitive tissues to ionizing radiation, thus, radiation-induced lung injury (RILI) stays a key dose-limiting factor of thoracic radiotherapy. However, there is still little progress in the effective treatment of RILI. Ras-related C3 botulinum toxin substrate1, Rac1, is a...

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Detalles Bibliográficos
Autores principales: An, Ni, Li, Zhenjie, Yan, Xiaodi, Zhao, Hainan, Yang, Yajie, Liu, Ruling, Yang, Yanyong, Gao, Fu, Li, Bailong, Liu, Hu, Yuan, Hongbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760284/
https://www.ncbi.nlm.nih.gov/pubmed/35031595
http://dx.doi.org/10.1038/s41420-021-00791-8