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KIAA0319 influences cilia length, cell migration and mechanical cell–substrate interaction

Following its association with dyslexia in multiple genetic studies, the KIAA0319 gene has been extensively investigated in different animal models but its function in neurodevelopment remains poorly understood. We developed the first human cellular knockout model for KIAA0319 in RPE1 retinal pigmen...

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Detalles Bibliográficos
Autores principales: Diaz, Rebeca, Kronenberg, Nils M., Martinelli, Angela, Liehm, Philipp, Riches, Andrew C., Gather, Malte C., Paracchini, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760330/
https://www.ncbi.nlm.nih.gov/pubmed/35031635
http://dx.doi.org/10.1038/s41598-021-04539-3