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Gene-environment-gut interactions in Huntington's disease mice are associated with environmental modulation of the gut microbiome

Gut dysbiosis in Huntington's disease (HD) has recently been reported using microbiome profiling in R6/1 HD mice and replicated in clinical HD. In HD mice, environmental enrichment (EE) and exercise (EX) were shown to have therapeutic impacts on the brain and associated symptoms. We hypothesize...

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Detalles Bibliográficos
Autores principales: Gubert, Carolina, Love, Chloe Jane, Kodikara, Saritha, Mei Liew, Jamie Jie, Renoir, Thibault, Lê Cao, Kim-Anh, Hannan, Anthony John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760441/
https://www.ncbi.nlm.nih.gov/pubmed/35059604
http://dx.doi.org/10.1016/j.isci.2021.103687