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DNA demethylase ALKBH1 promotes adipogenic differentiation via regulation of HIF-1 signaling

DNA N6-adenine methylation (6mA), as a novel adenine modification existing in eukaryotes, shows essential functions in embryogenesis and mitochondrial transcriptions. ALKBH1 is a demethylase of 6mA and plays critical roles in osteogenesis, tumorigenesis, and adaptation to stress. However, the integr...

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Detalles Bibliográficos
Autores principales: Liu, Yuting, Chen, Yaqian, Wang, Yuan, Jiang, Shuang, Lin, Weimin, Wu, Yunshu, Li, Qiwen, Guo, Yuchen, Liu, Weiqing, Yuan, Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760519/
https://www.ncbi.nlm.nih.gov/pubmed/34922943
http://dx.doi.org/10.1016/j.jbc.2021.101499